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The numbers are hard to estimate but as many as 25,000 or even more transgender people live in the United States. For those males redefining themselves as women the voice can be a difficult part of the transition. From member station KUOW in Seattle Cathy Duchamp reports on a voice therapy program designed to help them sound more feminine.

the lead singer of the punk band The Ramones. He died on Sunday at the age of 49. He had lymphoma. From their start in 1974, the Ramones combined fast, deafening guitar with precise drumming to create a hurricane of sound. Their songs had titles like Beat on the Brat, Gimme Gimme Shock Treatment and Now I Wanna Sniff Some Glue.

NPR's Jennifer Ludden in Gaza reports on the Israeli army's thrust into Palestinian-ruled territory. Israeli forces withdrew Tuesday from small areas of the Gaza Strip they seized Monday after an attempt to end Palestinian mortar attacks on Israeli towns and settlements.

NPR's Barbara Bradley reports on a federal judge's ruling that felons have a constitutional right to DNA evidence testing. The Virginia case involves James Harvey, who is serving a 25-year prison sentence for a 1990 rape he says he did not commit. He asked the state to do DNA testing on items of evidence, but Virginia refused. The judge ruled that the state must do the tests, as part of Harvey's right to due process. The ruling is believed to be the first of its kind in the federal courts.

The Bush administration plans to uphold regulations issued in the last weeks of Bill Clinton's presidency requiring thousands of more businesses to report their releases of toxic lead into the environment. NPR's John Nielsen reports on the details of the announcement by the Environmental Protection Agency's administrator, Christie Whitman.

Cisco Systems grew in breathtaking fashion to become one of the world's most valuable companies during the technology investment boom of the late '90s. But now Cisco is being hit hard by the economic slowdown. NPR's Jack Speer reports.

Linda Wertheimer talks with Jeremy Siegel, professor of finance at the Wharton School of Business at the University of Pennsylvania in Philadelphia, about the recent fluctuations of the stock market, and what's to be expected in the future.

In Pretoria this week, court action resumes in a lawsuit that pits 39 major pharmaceutical companies against the South African government and AIDS activists. The drug companies hope to block a law that allows South Africa to import or manufacture cheaper generic medications. NPR's Jon Hamilton reports on what's at stake for each of the major players in the case.

NPR's Ivan Watson in the city of Cotonou in the West African country of Benin reports on the mystery of the whereabouts of nearly 200 slave children. They were thought to have been on board a cargo vessel. But when the ship docked at Benin's main port, there was no sign of the child slaves.

NPR's Nina Totenberg reports on today's oral arguments before the Supreme Court on mushroom ads. A mushroom grower is trying to get out of paying a share of the cost of a national ad campaign organized by the government. United Foods says it can promote its product better with its own ads.